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Columbia NFL Draft Choices
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| Year | Round | Overall | Name | Team | Position | School |
| 1997 | 2 | 52 | Marcellus Wiley | Bills | DE | Columbia |
| 1984 | 6 | 160 | John Witkowski | Lions | QB | Columbia |
| 1971 | 11 | 272 | George Starke | Redskins | OT | Columbia |
| 1969 | 1 | 9 | Marty Domres | Chargers | QB | Columbia |
| 1967 | 16 | 401 | Jerry Zawadzkas | Lions | TE | Columbia |
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