A surprising questionable designation has led to a looming absence for the Titans' QB1, Bobby Kownack of NFL.com reports.

Will Levis will be inactive for Sunday's game against the Buffalo Bills due to a right shoulder injury, NFL Network Insider Tom Pelissero reported Saturday, meaning Mason Rudolph will get the start.

According to NFL Network Insider Ian Rapoport, Levis is dealing with a Grade 2 AC joint sprain and is considered week to week, so he could miss beyond the one contest.

Levis began the lead-up to Sunday's game as a limited practice participant on Wednesday, but after he practiced in full on Thursday as he had all the week prior, it seemed that was likely to rest his shoulder following his first game back after injuring it in Week 4 against the Dolphins.

Only Levis was again limited Friday, after which he received a questionable designation heading into the weekend.

Provided a Week 5 bye to recover initially, Tennessee's signal-caller had no designation ahead of the team's eventual 20-17 loss to the Colts in Week 6, a contest that again showcased Levis' inconsistencies as he completed just 59.3 percent of his 27 passes for 95 yards and a touchdown and interception apiece.

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