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Clemson NFL Draft Choices
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| Year | Round | Overall | Name | Team | Position | School |
| 2024 | 1 | 30 | Nate Wiggins | Ravens | CB | Clemson |
| 2024 | 2 | 35 | Ruke Orhorhoro | Falcons | DT | Clemson |
| 2024 | 4 | 127 | Will Shipley | Eagles | RB | Clemson |
| 2024 | 5 | 138 | Xavier Thomas | Cardinals | EDGE | Clemson |
| 2024 | 5 | 155 | Jeremiah Trotter Jr. | Eagles | LB | Clemson |
| 2024 | 6 | 196 | Tyler Davis | Rams | DT | Clemson |
| 2023 | 1 | 28 | Myles Murphy | Bengals | DE | Clemson |
| 2023 | 1 | 29 | Bryan Bresee | Saints | DT | Clemson |
| 2023 | 3 | 86 | Trenton Simpson | Ravens | LB | Clemson |
| 2023 | 5 | 137 | K.J. Henry | Commanders | DE | Clemson |
| 2023 | 5 | 175 | Davis Allen | Rams | TE | Clemson |
| 2022 | 2 | 42 | Andrew Booth Jr. | Vikings | CB | Clemson |
| 2022 | 7 | 231 | Baylon Spector | Bills | LB | Clemson |
| 2021 | 1 | 1 | Trevor Lawrence | Jaguars | QB | Clemson |
| 2021 | 1 | 25 | Travis Etienne | Jaguars | RB | Clemson |
| 2021 | 2 | 46 | Jackson Carman | Bengals | OT | Clemson |
| 2021 | 3 | 85 | Amari Rodgers | Packers | WR | Clemson |
| 2021 | 5 | 181 | Cornell Powell | Chiefs | WR | Clemson |
| 2020 | 1 | 8 | Isaiah Simmons | Cardinals | LB | Clemson |
| 2020 | 1 | 16 | A.J. Terrell | Falcons | CB | Clemson |
| 2020 | 2 | 33 | Tee Higgins | Bengals | WR | Clemson |
| 2020 | 3 | 100 | Tanner Muse | Raiders | S | Clemson |
| 2020 | 4 | 109 | John Simpson | Raiders | OT | Clemson |
| 2020 | 4 | 127 | K'Von Wallace | Eagles | S | Clemson |
| 2020 | 7 | 250 | Tremayne Anchrum | Rams | OG | Clemson |
| 2019 | 1 | 4 | Clelin Ferrell | Raiders | DE | Clemson |
| 2019 | 1 | 13 | Christian Wilkins | Dolphins | DT | Clemson |
| 2019 | 1 | 17 | Dexter Lawrence | Giants | DT | Clemson |
| 2019 | 2 | 40 | Trayvon Mullen | Raiders | CB | Clemson |
| 2019 | 4 | 117 | Austin Bryant | Lions | DE | Clemson |
| 2019 | 5 | 149 | Hunter Renfrow | Raiders | WR | Clemson |
| 2018 | 3 | 100 | Dorian O'Daniel | Chiefs | LB | Clemson |
| 2018 | 6 | 185 | Deon Cain | Colts | WR | Clemson |
| 2018 | 6 | 187 | Ray-Ray McCloud | Bills | WR | Clemson |
| 2017 | 1 | 7 | Mike Willams | Chargers | WR | Clemson |
| 2017 | 1 | 12 | DeShaun Watson | Texans | QB | Clemson |
| 2017 | 3 | 97 | Cordrea Tankersley | Dolphins | CB | Clemson |
| 2017 | 4 | 140 | Wayne Gallman | Giants | RB | Clemson |
| 2017 | 4 | 142 | Carlos Watkins | Texans | DT | Clemson |
| 2017 | 5 | 150 | Jordan Leggett | Jets | TE | Clemson |
| 2016 | 1 | 19 | Shaq Lawson | Bills | DE | Clemson |
| 2016 | 2 | 33 | Kevin Dodd | Titans | DE | Clemson |
| 2016 | 2 | 54 | Mackensie Alexander | Vikings | CB | Clemson |
| 2016 | 2 | 57 | T.J. Green | Colts | FS | Clemson |
| 2016 | 4 | 109 | B.J. Goodson | Giants | LB | Clemson |
| 2016 | 5 | 166 | D,J. Reader | Texans | DT | Clemson |
| 2016 | 7 | 241 | Charone Peake | Jets | WR | Clemson |
| 2016 | 7 | 244 | Jayron Kearse | Vikings | S | Clemson |
| 2016 | 7 | 247 | Zac Brooks | Seahawks | RB | Clemson |
| 2015 | 1 | 8 | Vic Beasley | Falcons | LB | Clemson |
| 2015 | 1 | 31 | Stephone Anthony | Saints | LB | Clemson |
| 2015 | 5 | 137 | Grady Jarrett | Falcons | DT | Clemson |
| 2015 | 5 | 165 | Bradley Pinion | 49ers | P | Clemson |
| 2015 | 6 | 188 | Tony Steward | Bills | LB | Clemson |
| 2014 | 1 | 4 | Sammy Watkins | Bills | WR | Clemson |
| 2014 | 3 | 100 | Brandon Thomas | 49ers | OT | Clemson |
| 2014 | 4 | 102 | Bashaud Breeland | Commanders | CB | Clemson |
| 2014 | 4 | 118 | Martavis Bryant | Steelers | WR | Clemson |
| 2014 | 6 | 213 | Tajh Boyd | Jets | QB | Clemson |
| 2013 | 1 | 27 | DeAndre Hopkins | Texans | WR | Clemson |
| 2013 | 4 | 127 | Malliciah Goodman | Falcons | DE | Clemson |
| 2013 | 5 | 143 | Jonathan Meeks | Bills | S | Clemson |
| 2013 | 6 | 187 | Andre Ellington | Cardinals | RB | Clemson |
| 2012 | 2 | 38 | Andre Branch | Jaguars | DE | Clemson |
| 2012 | 3 | 64 | Dwayne Allen | Colts | TE | Clemson |
| 2012 | 3 | 93 | Brandon Thompson | Bengals | DT | Clemson |
| 2012 | 4 | 115 | Coty Sensabaugh | Titans | CB | Clemson |
| 2011 | 2 | 41 | Jarvis Jenkins | Commanders | DT | Clemson |
| 2011 | 2 | 50 | Marcus Gilchrist | Chargers | S | Clemson |
| 2011 | 4 | 122 | Chris Hairston | Bills | OT | Clemson |
| 2011 | 4 | 130 | Jamie Harper | Titans | RB | Clemson |
| 2011 | 6 | 173 | Byron Maxwell | Seahawks | CB | Clemson |
| 2010 | 1 | 9 | C.J. Spiller | Bills | RB | Clemson |
| 2010 | 4 | 108 | Jacoby Ford | Raiders | WR | Clemson |
| 2010 | 5 | 134 | Ricky Sapp | Eagles | DE | Clemson |
| 2010 | 5 | 164 | Crezdon Butler | Steelers | CB | Clemson |
| 2010 | 7 | 240 | Kavell Conner | Colts | LB | Clemson |
| 2009 | 4 | 103 | Dorrell Scott | Rams | DT | Clemson |
| 2009 | 5 | 165 | Chris Clemons | Dolphins | S | Clemson |
| 2009 | 5 | 166 | Michael Hamlin | Cowboys | S | Clemson |
| 2009 | 6 | 195 | James Davis | Browns | RB | Clemson |
| 2008 | 2 | 32 | Phillip Merling | Dolphins | DE | Clemson |
| 2008 | 6 | 170 | Barry Richardson | Chiefs | OT | Clemson |
| 2007 | 1 | 4 | Gaines Adams | Buccaneers | DE | Clemson |
| 2007 | 3 | 96 | Anthony Waters | Chargers | LB | Clemson |
| 2007 | 5 | 139 | Dustin Fry | Rams | C | Clemson |
| 2007 | 5 | 159 | C.J. Gaddis | Eagles | CB | Clemson |
| 2007 | 7 | 235 | Chansi Stuckey | Jets | WR | Clemson |
| 2006 | 1 | 15 | Tye Hill | Rams | CB | Clemson |
| 2006 | 3 | 81 | Charlie Whitehurst | Chargers | QB | Clemson |
| 2006 | 7 | 241 | Charles Bennett | Buccaneers | DE | Clemson |
| 2005 | 2 | 57 | Justin Miller | Jets | CB | Clemson |
| 2005 | 3 | 98 | LeRoy Hill | Seahawks | LB | Clemson |
| 2005 | 5 | 140 | Airese Currie | Bears | WR | Clemson |
| 2004 | 3 | 72 | Donnell Washington | Packers | DT | Clemson |
| 2004 | 3 | 77 | Derrick Hamilton | 49ers | WR | Clemson |
| 2003 | 4 | 114 | Nicholas Eason | Broncos | DT | Clemson |
| 2003 | 4 | 128 | Bryant McNeal | Broncos | DE | Clemson |
| 2001 | 1 | 15 | Rod Gardner | Commanders | WR | Clemson |
| 2001 | 7 | 232 | Keith Adams | Titans | LB | Clemson |
| 2001 | 7 | 244 | Robert Carswell | Chargers | DB | Clemson |
| 1999 | 1 | 25 | Antwan Edwards | Packers | DB | Clemson |
| 1999 | 2 | 45 | Rahim Abdullah | Browns | LB | Clemson |
| 1999 | 5 | 139 | Adrian Dingle | Chargers | DE | Clemson |
| 1999 | 5 | 169 | Chris Jones | Vikings | LB | Clemson |
| 1999 | 7 | 231 | O.J. Childress | Giants | LB | Clemson |
| 1999 | 7 | 249 | Donald Broomfield | Bengals | DE | Clemson |
| 1998 | 1 | 15 | Anthony Simmons | Seahawks | LB | Clemson |
| 1998 | 4 | 102 | Lorenzo Bromell | Dolphins | DT | Clemson |
| 1998 | 5 | 129 | Raymond Priester | Rams | RB | Clemson |
| 1998 | 6 | 159 | Glenn Rountree | Rams | OG | Clemson |
| 1998 | 7 | 210 | Jim Bundren | Dolphins | OG | Clemson |
| 1997 | 1 | 28 | Trevor Pryce | Broncos | DE | Clemson |
| 1997 | 2 | 40 | Dexter McCleon | Rams | DB | Clemson |
| 1996 | 2 | 50 | Patrick Sapp | Chargers | LB | Clemson |
| 1996 | 2 | 61 | Brian Dawkins | Eagles | DB | Clemson |
| 1996 | 5 | 138 | Leomont Evans | Commanders | DB | Clemson |
| 1995 | 6 | 179 | Wardell Rouse | Buccaneers | LB | Clemson |
| 1994 | 2 | 50 | Brentson Buckner | Steelers | DE | Clemson |
| 1994 | 7 | 203 | Andre Hewitt | Browns | OT | Clemson |
| 1993 | 1 | 15 | Wayne Simmons | Packers | LB | Clemson |
| 1993 | 3 | 72 | James Trapp | Raiders | DB | Clemson |
| 1993 | 4 | 91 | Rudy Harris | Buccaneers | RB | Clemson |
| 1993 | 4 | 106 | Ashley Sheppard | Vikings | LB | Clemson |
| 1993 | 6 | 164 | Robert O'Neal | Dolphins | DB | Clemson |
| 1992 | 1 | 16 | Chester McGlockton | Raiders | DT | Clemson |
| 1992 | 2 | 38 | Levon Kirkland | Steelers | LB | Clemson |
| 1992 | 5 | 117 | Curtis Whitley | Chargers | C | Clemson |
| 1992 | 5 | 125 | Ed McDaniel | Vikings | LB | Clemson |
| 1991 | 2 | 41 | Jerome Henderson | Patriots | DB | Clemson |
| 1991 | 2 | 51 | Doug Thomas | Seahawks | WR | Clemson |
| 1991 | 2 | 53 | John Johnson | 49ers | LB | Clemson |
| 1991 | 3 | 78 | Chris Gardocki | Bears | P | Clemson |
| 1991 | 4 | 86 | Dexter Davis | Cardinals | DB | Clemson |
| 1991 | 5 | 117 | Vance Hammond | Cardinals | DT | Clemson |
| 1991 | 10 | 271 | Eric Harmon | Eagles | OG | Clemson |
| 1991 | 11 | 301 | Stacy Long | Bears | OG | Clemson |
| 1990 | 9 | 241 | Terry Allen | Vikings | RB | Clemson |
| 1990 | 10 | 260 | Gary Cooper | Saints | WR | Clemson |
| 1990 | 10 | 274 | Otis Moore | Giants | DT | Clemson |
| 1989 | 1 | 11 | Donnell Woolford | Bears | DB | Clemson |
| 1989 | 4 | 97 | Richad McCullough | Broncos | DE | Clemson |
| 1989 | 5 | 113 | Keith Jennings | Cowboys | TE | Clemson |
| 1989 | 10 | 257 | Ty Granger | Buccaneers | OT | Clemson |
| 1989 | 10 | 271 | Tracy Johnson | Oilers | RB | Clemson |
| 1988 | 2 | 50 | Michael Dean Perry | Browns | DT | Clemson |
| 1988 | 3 | 81 | Tony Stephens | Saints | DT | Clemson |
| 1988 | 12 | 322 | James Earle | Steelers | LB | Clemson |
| 1987 | 1 | 25 | Terrence Flagler | 49ers | RB | Clemson |
| 1987 | 2 | 31 | Kenny Flowers | Falcons | RB | Clemson |
| 1987 | 2 | 38 | Delton Hall | Steelers | DB | Clemson |
| 1987 | 4 | 103 | Jim Riggs | Bengals | TE | Clemson |
| 1985 | 1 | 22 | William Perry | Bears | DT | Clemson |
| 1985 | 3 | 58 | Tyrone Davis | Giants | DB | Clemson |
| 1985 | 3 | 77 | Dale Hatcher | Rams | P | Clemson |
| 1985 | 5 | 116 | K.D. Dunn | Cardinals | TE | Clemson |
| 1985 | 6 | 152 | Reggie Pleasant | Falcons | DB | Clemson |
| 1985 | 10 | 260 | Donald Igwebuike | Buccaneers | K | Clemson |
| 1984 | 3 | 63 | Rod McSwain | Falcons | DB | Clemson |
| 1984 | 6 | 143 | Jim Scott | Giants | DE | Clemson |
| 1984 | 8 | 213 | Bob Paulling | Cardinals | K | Clemson |
| 1984 | 11 | 295 | Edgar Pickett | Vikings | LB | Clemson |
| 1984 | 12 | 320 | William Devane | Dolphins | DT | Clemson |
| 1984 | 12 | 326 | Murray Jarman | Broncos | WR | Clemson |
| 1983 | 1 | 10 | Terry Kinard | Giants | DB | Clemson |
| 1983 | 3 | 66 | Cliff Astin | Saints | RB | Clemson |
| 1983 | 4 | 101 | Johnny Rembert | Patriots | LB | Clemson |
| 1983 | 5 | 135 | Chuck McSwain | Cowboys | RB | Clemson |
| 1983 | 7 | 194 | Jeff McCall | Raiders | RB | Clemson |
| 1983 | 8 | 205 | Andy Headen | Giants | LB | Clemson |
| 1983 | 11 | 282 | Danny Triplett | Rams | LB | Clemson |
| 1983 | 11 | 290 | Bob Mayberry | Seahawks | OG | Clemson |
| 1983 | 11 | 298 | Brian Butcher | Vikings | OG | Clemson |
| 1983 | 12 | 318 | Frank Magwood | Giants | WR | Clemson |
| 1982 | 1 | 6 | Jeff Bryant | Seahawks | DE | Clemson |
| 1982 | 1 | 19 | Perry Tuttle | Bills | WR | Clemson |
| 1982 | 5 | 128 | Jeff David | Buccaneers | LB | Clemson |
| 1982 | 7 | 188 | Hollis Hall | Chargers | DB | Clemson |
| 1982 | 9 | 225 | Tony Berryhill | Colts | C | Clemson |
| 1982 | 12 | 327 | Brian Clark | Broncos | OG | Clemson |
| 1981 | 6 | 140 | Steve Durham | Seahawks | DE | Clemson |
| 1981 | 7 | 178 | Obed Ariri | Colts | K | Clemson |
| 1980 | 1 | 20 | Jim Stuckey | 49ers | DT | Clemson |
| 1980 | 7 | 189 | Lester Brown | Cowboys | RB | Clemson |
| 1980 | 12 | 324 | Marvin Sims | Colts | RB | Clemson |
| 1979 | 1 | 5 | Jerry Butler | Bills | WR | Clemson |
| 1979 | 1 | 23 | Steve Fuller | Chiefs | QB | Clemson |
| 1979 | 3 | 64 | Joe Bostic | Cardinals | OT | Clemson |
| 1979 | 4 | 92 | Jonathan Brooks | Lions | LB | Clemson |
| 1979 | 10 | 249 | Dwight Clark | 49ers | WR | Clemson |
| 1979 | 11 | 277 | Stan Rome | Chiefs | WR | Clemson |
| 1978 | 5 | 127 | Archie Reese | 49ers | DT | Clemson |
| 1978 | 8 | 213 | Roy Eppes | Jets | DB | Clemson |
| 1978 | 11 | 305 | Lacy Brumley | Broncos | OT | Clemson |
| 1976 | 1 | 28 | Bennie Cummingham | Steelers | TE | Clemson |
| 1976 | 10 | 282 | Don Testerman | Dolphins | RB | Clemson |
| 1976 | 11 | 303 | Craig Brantley | Giants | WR | Clemson |
| 1976 | 15 | 424 | Gary Alexander | Colts | OT | Clemson |
| 1974 | 6 | 131 | Jim Washington | Chiefs | RB | Clemson |
| 1973 | 6 | 155 | Rick Harrell | Jets | C | Clemson |
| 1973 | 11 | 266 | Ed Siegler | Bears | K | Clemson |
| 1972 | 3 | 63 | John McMakin | Steelers | TE | Clemson |
| 1972 | 9 | 217 | Don Kelley | Steelers | DB | Clemson |
| 1972 | 14 | 346 | Larry Hefner | Packers | LB | Clemson |
| 1971 | 2 | 30 | Dave Thompson | Lions | C | Clemson |
| 1970 | 3 | 66 | Charlie Waters | Cowboys | DB | Clemson |
| 1970 | 11 | 283 | Ivan Southerland | Cowboys | OT | Clemson |
| 1970 | 14 | 347 | Jack King | 49ers | OG | Clemson |
| 1969 | 8 | 201 | Wayne Mulligan | Cardinals | C | Clemson |
| 1969 | 14 | 344 | John Cagle | Patriots | LB | Clemson |
| 1968 | 3 | 64 | Harry Olszewski | Browns | OG | Clemson |
| 1968 | 4 | 99 | Wayne Mass | Bears | OT | Clemson |
| 1968 | 5 | 134 | Jackie Jackson | Browns | RB | Clemson |
| 1968 | 9 | 230 | Frank Liberatore | Commanders | DB | Clemson |
| 1967 | 14 | 360 | Floyd Rogers | Browns | OT | Clemson |
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