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Northwestern State NFL Draft Choices
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| Year | Round | Overall | Name | Team | Position | School |
| 2015 | 7 | 223 | Deon Simon | Jets | DT | Northwestern State |
| 2012 | 6 | 172 | Jeremy Lane | Seahawks | CB | Northwestern State |
| 2008 | 7 | 219 | Demetrius Bell | Bills | OT | Northwestern State |
| 2006 | 3 | 87 | David Pittman | Ravens | CB | Northwestern State |
| 2006 | 7 | 253 | Dave Tollefson | Packers | DE | Northwestern State |
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