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Prairie View NFL Draft Choices
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| Year | Round | Overall | Name | Team | Position | School |
| 1980 | 10 | 273 | Matthew Teague | Cowboys | DE | Prairie View |
| 1974 | 6 | 149 | James Wolf | Steelers | DE | Prairie View |
| 1974 | 16 | 416 | Jessie Wolf | Dolphins | DT | Prairie View |
| 1973 | 5 | 124 | Louis Neal | Raiders | WR | Prairie View |
| 1973 | 8 | 202 | Hise Austin | Packers | DB | Prairie View |
| 1971 | 3 | 54 | Bivian Lee | Saints | DB | Prairie View |
| 1971 | 15 | 367 | Ed Fisher | Eagles | OG | Prairie View |
| 1971 | 17 | 431 | Travis Hill | Chiefs | DB | Prairie View |
| 1970 | 2 | 35 | Charles Williams | Rams | WR | Prairie View |
| 1969 | 4 | 81 | James Mitchell | Falcons | TE | Prairie View |
| 1969 | 7 | 178 | Finnis Taylor | Raiders | DB | Prairie View |
| 1969 | 8 | 196 | Glenn Woods | Oilers | DE | Prairie View |
| 1969 | 11 | 283 | Clarence Williams | Cowboys | DT | Prairie View |
| 1969 | 16 | 413 | Eural Johnson | Chiefs | DB | Prairie View |
| 1968 | 11 | 280 | Cornelius Cooper | Dolphins | OT | Prairie View |
| 1968 | 13 | 343 | Willie Dearlon | Bears | WR | Prairie View |
| 1967 | 9 | 214 | Ken Houston | Oilers | DB | Prairie View |
| 1967 | 9 | 224 | Ray Scott | Jets | DE | Prairie View |
| 1967 | 13 | 329 | Leon Carr | Chargers | DB | Prairie View |
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