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San Francisco 49ers Get Brutal Injury Update On 2 Of Their Biggest Superstars Ahead Of Week 18 vs. Seahawks

This article was originally published on Total Pro Sports.

Detail view of the helmet for San Francisco 49ers helmet
Detail view of the helmet for San Francisco 49ers helmet (Kyle Terada-Imagn Images)

Will George Kittle and Trent Williams be available for the final game for the San Francisco 49ers?

In Week 18, the 49ers are playing for the NFC West division title. They return to Levi’s Stadium in Week 18 to host the Seattle Seahawks on Saturday. Having a full roster is going to be key for a game of this magnitude.

This game also holds a lot of significance for the road team as well. If Seattle defeats the 49ers, Seattle will claim the NFC’s No. 1 seed and the conference’s lone first-round bye. And if the Seahawks lose, they will be guaranteed to be the No. 5 seed.

Ian Rapoport Gives Update On San Francisco 49ers Star Players

Detail view of a helmet for San Francisco 49ers
Detail view of the helmet for San Francisco 49ers (Kyle Terada-Imagn Images)

NFL Network Insider Ian Rapoport gave a massive update on this contest. Tight end George Kittle has dealt with his fair share of injuries in 2025.

George Kittle and wide receiver Jauan Jennings were injured in the season opener. Kittle was also placed on the injured reserve after suffering a hamstring injury. That injury came against the Seahawks.

The concern for the San Francisco 49ers was his ankle for the final game of the year. Ian Rapoport reported that the star will “absolutely” play in this contest. However, he hasn’t been listed as a full participant in practice as of yet. That is the only thing that remains up in the air.

President of Football Operations John Lynch also spoke on Kittle. He said he would be “very surprised” if the veteran tight end misses this week’s game against Seattle.

Rapoport also spoke on Trent Williams. He hasn’t practiced due to his hamstring injury, and the insider believes he will not play against Seattle.

Kittle has had another very productive season with the 49ers, catching 52 passes for 599 yards through 10 games. He remains one of Brock Purdy’s favorite red-zone targets. As long as the San Francisco 49ers have him, they are in a great position.

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